American cancer society

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For most of the cancers, it cannot be told which event was the initial cause. However, with molecular biology, it is possible to characterize the mutations within a tumor, and to a certain extent predict its behavior. For example, about half of the tumors are deficient in the tumor suppressor gene p53, also known as "the guardian of the genome". This is associated with poor prospects for the patient, since those tumor cells are unlikely to go into apoptosis (programmed cell death) after they are damaged by therapy. There are more mutations that make a tumor more malignant. Telomerase mutations enable a tumor cell to divide indefinitely. Other mutations enable the tumor to grow new blood vessels to feed it, or to detach from the surrounding tissue, spreading to other parts of the body.

Carcinogenesis (lit.: creation of cancer) is the process of derangement of the rate of cell division.

The field of medicine concerned with the treatment of cancer is oncology. Cancer has become an important problem with the rise in life expectancy, as the abovementioned mutations become more likely the longer a person lives. Though great progress in treatment has been made, most cancers in advanced stages remain incurable and ultimately fatal.

  • Don't Say That Word
    Provides an online forum on cancer, information, personal stories, poetry and remembrance pages. Graphics-intensive.
  • Cancer Nutrition Center
    Explores the link between tumors and nutrition. Offers dietary advice for patients.
  • OncoLink
    Extensive information including news, prevention, clinical trials, conferences and psychosocial support from the University of Pennsylvania Cancer Center.
  • Cancer Advice UK
    Advice and information about diagnosis and treatment issues. Includes leaflets, book suggestions, links and support groups.
  • CancerFit
    Details the activities of a program at the Sedona Racquet Club in Arizona. Designed to help survivors maintain good physical, emotional and spiritual fitness.