Cancer zodiac

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In cellular model systems, cells are exposed to carcinogenic influences (chemicals, radiation). In these systems, the first signs of a cell developing into a tumor cell are:

  • Immortality. The usual number of cell divisions for a mammalian cell is 50-60 (cell senescence), then it ceases to divide. Tumor cells keep dividing forever.
  • Altered morphology.
  • Building of cellular clusters (Foci).
  • Loss of contact inhibition.
  • Low or no need for growth factors.

Items 2-4 (above) can sometimes be traced to mutations in genes that result in a disruption of cell adhesion. Some cell adhesion proteins are oncogenes.

In medicine, cancer is a general term for any of a number of different diseases where some of the body's own cells divide in an uncontrolled manner. The resulting new cells can form a malignant tumor (a neoplasm) or propagate throughout the body.

The field of medicine concerned with the treatment of cancer is oncology. Cancer has become an important problem with the rise in life expectancy, as the abovementioned mutations become more likely the longer a person lives. Though great progress in treatment has been made, most cancers in advanced stages remain incurable and ultimately fatal.

  • A Notebook Guide For Newly Diagnosed Cancer Patients
    Information for people who have just received the diagnosis. Includes links, a message board and details about the author.
  • DIPEx: Cancer
    Includes audio and video interviews of patient experiences.
  • Cancer.com
    Provides treatment information, support group listings, online education, decision-making resources, physician locator services and risk assessment tools.
  • The "Y" Cancer Foundation
    AOL discussion group aimed at providing information and support.
  • MedicineNet: Cancer
    Presents information such as prevention and treatment side-effects. Also gives resources including links, articles and support groups.