Squamous cell cancer

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Treatment of cancer typically involves surgery to remove tumors and nearby lymph nodes to which the cancer may have spread, combined with radiation therapy and/or chemotherapy. The latter two target cells in the body that are rapidly dividing. This includes the cancer cells but also certain healthy ones, which is the reason for the severe side effects of these treatments.

The term cancer is very broad and covers many different illnesses including:

  • Carcinoma (arising from epithelial cells)
  • Bladder carcinoma
  • Breast cancer
  • Cervical cancer
  • Colorectal cancer (includes colon, rectum, anus, and appendix)
  • Esophageal cancer
  • Endometrial cancer (uterus)
  • Hepatocellular carcinoma (liver)
  • Laryngeal cancer
  • Lung cancer
  • Oral cancer
  • Ovarian cancer
  • Pancreatic cancer
  • Prostate cancer
  • Renal cell carcinoma (kidney)
  • Skin cancer
  • Stomach cancer
  • Testicular cancer
  • Thyroid cancer
  • Sarcoma (arising from connective tissue and related)
  • Gastrointestinal stromal cell tumor (GIST)
  • Rhabdomyosarcoma (muscle)
  • Osteosarcoma (bone)
  • Hematological malignancies (blood and bone marrow)
  • Leukemia
  • Lymphomas
  • Hodgkin's disease
  • Non-Hodgkin's lymphoma
  • Multiple myeloma
  • Miscellaneous
  • Brain tumor
  • Melanoma, Moles and dysplastic nevi
  • Teratoma

A cell that degenerates into a tumor cell does usually not acquire all these properties at once, but its daughter cells are selected to build them. This process is called cellular evolution. A first step in the development of a tumor cell is usually a small change in the DNA, often a point mutation, which leads, among other things, to a genetic instability of the cell. The instability increases to a point where the cell loses whole chromosomes, or has double ones. Also, the DNA methylation pattern of the cell changes, activating and deactivating genes more or less at random. Cells that divide at a high rate, such as stem cells, show a higher risk of becoming tumor cells than those which divide less or not at all, for example neurons. If the initial tumor cell (or group of tumor cells) is not removed by the immune system, it will develop into cancer.

  • Cancer Network.com
    Information resource aimed at health professionals. Requires registration.
  • Yahoo Health: Radiation Therapy Center
    Information including basic facts, what to expect and side effects.
  • CancerSource
    Provides information about prevention, detection, diagnosis, treatment and symptom management. Offers access to news, support groups and email lists.
  • Cancer Page
    Information and community resources including chat rooms, message boards, physician directory and clinical trials.
  • DIPEx: Cancer
    Includes audio and video interviews of patient experiences.