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In medicine, cancer is a general term for any of a number of different diseases where some of the body's own cells divide in an uncontrolled manner. The resulting new cells can form a malignant tumor (a neoplasm) or propagate throughout the body.

The field of medicine concerned with the treatment of cancer is oncology. Cancer has become an important problem with the rise in life expectancy, as the abovementioned mutations become more likely the longer a person lives. Though great progress in treatment has been made, most cancers in advanced stages remain incurable and ultimately fatal.

For most of the cancers, it cannot be told which event was the initial cause. However, with molecular biology, it is possible to characterize the mutations within a tumor, and to a certain extent predict its behavior. For example, about half of the tumors are deficient in the tumor suppressor gene p53, also known as "the guardian of the genome". This is associated with poor prospects for the patient, since those tumor cells are unlikely to go into apoptosis (programmed cell death) after they are damaged by therapy. There are more mutations that make a tumor more malignant. Telomerase mutations enable a tumor cell to divide indefinitely. Other mutations enable the tumor to grow new blood vessels to feed it, or to detach from the surrounding tissue, spreading to other parts of the body.

  • Cancer Matters
    Contains information, treatment options, and resources on a range of cancers. Also includes links to general resources, and a directory of services and resources located in a number of US cities.
  • CancerSource
    Provides information about prevention, detection, diagnosis, treatment and symptom management. Offers access to news, support groups and email lists.
  • Conversations In Care
    Explores the challenges surrounding physician and patient communications in cancer.
  • Don't Say That Word
    Provides an online forum on cancer, information, personal stories, poetry and remembrance pages. Graphics-intensive.
  • CancerTrack
    Access to related news, books and links.