Squamous cell cancer

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Cancer is, ultimately, a disease of genes. Typically, a series of several mutations is required before a cell becomes a cancer cell. We distinguish between oncogenes, which promote cancer when "switched on" by a mutation, and tumor suppressor genes, which prevent cancer unless "switched off" by a mutation. These mutations can have various causes: radiation or chemicals called carcinogens; some inherited predisposition is not uncommon; some viruses that can cause cancer have also been described. Usually, they carry in their genome some oncogene or tumor suppressor inactivating gene. In about 15% of all cancers, viruses seem to play a role; Bacteria, like Helicobacter pylori, also induce carcinogenesis by a process of chronic inflammation. Finally, damage by free radicals, which are a natural by-product of oxygen metabolism, can cause mutations in the DNA.

Treatment of cancer typically involves surgery to remove tumors and nearby lymph nodes to which the cancer may have spread, combined with radiation therapy and/or chemotherapy. The latter two target cells in the body that are rapidly dividing. This includes the cancer cells but also certain healthy ones, which is the reason for the severe side effects of these treatments.

The term cancer is very broad and covers many different illnesses including:

Carcinoma (arising from epithelial cells)
Bladder carcinoma
Breast cancer
Cervical cancer
Colorectal cancer (includes colon, rectum, anus, and appendix)
Esophageal cancer
Endometrial cancer (uterus)
Hepatocellular carcinoma (liver)
Laryngeal cancer
Lung cancer
Oral cancer
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cell carcinoma (kidney)
Skin cancer
Stomach cancer
Testicular cancer
Thyroid cancer
Sarcoma (arising from connective tissue and related)
Gastrointestinal stromal cell tumor (GIST)
Rhabdomyosarcoma (muscle)
Osteosarcoma (bone)
Hematological malignancies (blood and bone marrow)
Leukemia
Lymphomas
Hodgkin's disease
Non-Hodgkin's lymphoma
Multiple myeloma
Miscellaneous
Brain tumor
Melanoma, Moles and dysplastic nevi
Teratoma

The Cancer Letter
Periodical which supplies news and current information about the state of research and treatment.
World Oncology Network
World directory of cancer specialists and hematologists.
Topix.net: Cancer News
Headline news and content on related issues.
Cancer Information Services
Information from the U.S. National Cancer Institute including access to links, press releases and publications.
Cancer Mondial
The International Agency for Research on Cancer provides access to reports and databases on occurrence and characteristics.

Squamous cell cancer