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There are reports indicating that studies have shown benefits for heartstroke as well as diabetic patients, and that many experts are already discussing a low carb nutrition for diabetic patients who may then be able to live their lives without any insulin. Like any diet, the health effects will depend a great deal on the food choices one makes to meet the macronutrient requirements specified by the diet.

After the initial two week period, carbohydrate intake is gradually increased until it reaches a level at which the dieter loses weight slowly and can reduce or eliminate the supplements. Once the target weight is reached, carbohydrate levels are again gradually increased until the dieter's weight becomes stable. Each of these carbohydrate levels varies from person to person. Dr. Atkins argues that many eating disorders are the result of hyperinsulinism, or excessive secretion of insulin, which, according to Atkins, causes food cravings and unstable blood sugar levels. Atkins claims that his diet stabilizes insulin and blood sugar levels, eliminating cravings and often reducing appetite.

Atkins recommends restriction of the intake of carbohydrates in order to switch the body metabolism from using glucose as the fuel to burning fat (both dietary and stored fat). This process of lipolysis begins when the body enters the state of ketosis as a consequence of running out of carbohydrates to burn.