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The Very Low Calorie Diet, or VLCD, is a special diet to be undertaken with medical supervision. It offers rapid fat loss over a short timeframe, but can be dangerous for some people. It consists of the consumption of a special powder mixed in with 200-300ml of water to be taken three times a day. The drink, similar to a milkshake, provides approximately 1914Kj (456 Cal) of energy per day when consumed at breakfast, lunch and dinner. It contains all necessary vitamins and minerals, although there is a risk of overdosing on Selenium if a person consumes more than they should (more than three times per day). VLCD's should only be used for dieting when a person's Body mass index exceeds 30. In addition, at least 2 litres of water must be consumed per day and a person should consider using fibre supplements regularly. Without this, the person risks severe constipation.

Successful weight loss diet is all about energy in vs. energy out. If a person takes in fewer calories than he or she expends over a period of time, the person may burn fat and subsequently lose weight. To lose a pound of fat, one must create a caloric deficit of approximately 3,500 calories; therefore, if a person creates a deficit of 500 calories per day, the person will lose approximately 1 pound of fat per week. However, these numbers are strictly "in theory," and again what works for one person usually will not work for all.

The only "safe" method of weight loss is to eat a sensible healthy diet with a moderately decreased caloric intake from your norm, and to increase exercise gradually until weight loss results. It should be noted that people may follow these guidelines and not actually lose weight, but may see health improvements.