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The cuticle is responsible for much of the mechanical strength of the hair fibre. It consists of scale-shaped layers. Human hair typically has 6-8 layers of cuticle. Wool has only one, and other animal hair may have many more layers. Hair responds to its environment, and to its mechanical and chemical history. For example, hair which is wetted, styled and then dried, acquires a temporary 'set', which can hold it in style. This style is lost when the hair gets wet again. For more permanent styling, chemical treatments (perms) break and re-form the disulphide links within the hair structure.

On most adult humans there are two main types of hair: terminal hair, and vellus hair. A third type, lanugo hair, is present in the fetus, and some newborn babies.

Terminal hair grows thick and long, and is what grows on the head, armpits and pubic area, as well as on the face, chest, arms and legs (better evident in men).