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Hair is a biological polymer; over 90% of its dry weight is made up of proteins called keratins. Under normal conditions, human hair contains around 10% water, which modifies its mechanical properties considerably. Hair proteins are held together by disulfide bonds, from the amino acid cysteine. These links are very robust; for example, virtually intact hair has been recovered from ancient Egyptian tombs. Different parts of the hair have different cysteine levels, leading to harder or softer material.

Hair is an outgrowth of the epidermis in mammals. Hair is a characteristic of all mammals, though in some species hair is absent at certain stages of life.

The diameter of a human hair ranges from about 18 µm to 180 µm. In people of European descent, blond hair and black hair are at the thinner end of the scale, while red hair is the thickest. The hair of people of African descent is typically thicker than the hair of other groups.