American cancer society

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Cancer is, ultimately, a disease of genes. Typically, a series of several mutations is required before a cell becomes a cancer cell. We distinguish between oncogenes, which promote cancer when "switched on" by a mutation, and tumor suppressor genes, which prevent cancer unless "switched off" by a mutation. These mutations can have various causes: radiation or chemicals called carcinogens; some inherited predisposition is not uncommon; some viruses that can cause cancer have also been described. Usually, they carry in their genome some oncogene or tumor suppressor inactivating gene. In about 15% of all cancers, viruses seem to play a role; Bacteria, like Helicobacter pylori, also induce carcinogenesis by a process of chronic inflammation. Finally, damage by free radicals, which are a natural by-product of oxygen metabolism, can cause mutations in the DNA.

Carcinogenesis (lit.: creation of cancer) is the process of derangement of the rate of cell division.

The field of medicine concerned with the treatment of cancer is oncology. Cancer has become an important problem with the rise in life expectancy, as the abovementioned mutations become more likely the longer a person lives. Though great progress in treatment has been made, most cancers in advanced stages remain incurable and ultimately fatal.

EMedicine Health: What You Need To Know
Consumer health resource center providing general information on cancer prevention, symptoms and treatment.
Cancer Leadership Council
A patient-centered forum of national advocacy organizations addressing public policy issues.
CancerSupport UK
An online directory of resources.
Cancer Forums
Online discussions on various types of cancers. Includes topics such as coping, support, clinical trials and treatment options.
Target Tumors
Information about targeted therapy approach in relation to a number of solid tumors.

American cancer society