Bone marrow cancer
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Carcinogenesis (lit.: creation of cancer) is the process of derangement of the rate of cell division.
A cell that degenerates into a tumor cell does usually not acquire all these properties at once, but its daughter cells are selected to build them. This process is called cellular evolution. A first step in the development of a tumor cell is usually a small change in the DNA, often a point mutation, which leads, among other things, to a genetic instability of the cell. The instability increases to a point where the cell loses whole chromosomes, or has double ones. Also, the DNA methylation pattern of the cell changes, activating and deactivating genes more or less at random. Cells that divide at a high rate, such as stem cells, show a higher risk of becoming tumor cells than those which divide less or not at all, for example neurons. If the initial tumor cell (or group of tumor cells) is not removed by the immune system, it will develop into cancer.
In medicine, cancer is a general term for any of a number of different diseases where some of the body's own cells divide in an uncontrolled manner. The resulting new cells can form a malignant tumor (a neoplasm) or propagate throughout the body.
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- Cancer Survivors Project
A community resource for long term survivors. Includes access to the ACOR email discussion group. - Cancer.com
Provides treatment information, support group listings, online education, decision-making resources, physician locator services and risk assessment tools. - Meds.com: Cancer Glossary
Aims to provide a better understanding of words frequently used in patient care. - Cancer Network.com
Information resource aimed at health professionals. Requires registration. - Nexcura: Cancer Facts
Provides current information and access to a clinical trials profiler.