Bowel cancer
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Carcinogenesis (lit.: creation of cancer) is the process of derangement of the rate of cell division.
A cell that degenerates into a tumor cell does usually not acquire all these properties at once, but its daughter cells are selected to build them. This process is called cellular evolution. A first step in the development of a tumor cell is usually a small change in the DNA, often a point mutation, which leads, among other things, to a genetic instability of the cell. The instability increases to a point where the cell loses whole chromosomes, or has double ones. Also, the DNA methylation pattern of the cell changes, activating and deactivating genes more or less at random. Cells that divide at a high rate, such as stem cells, show a higher risk of becoming tumor cells than those which divide less or not at all, for example neurons. If the initial tumor cell (or group of tumor cells) is not removed by the immune system, it will develop into cancer.
In medicine, cancer is a general term for any of a number of different diseases where some of the body's own cells divide in an uncontrolled manner. The resulting new cells can form a malignant tumor (a neoplasm) or propagate throughout the body.
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- A Notebook Guide For Newly Diagnosed Cancer Patients
Information for people who have just received the diagnosis. Includes links, a message board and details about the author. - Conversations In Care
Explores the challenges surrounding physician and patient communications in cancer. - Cancer Leadership Council
A patient-centered forum of national advocacy organizations addressing public policy issues. - Cancer Forums
Online discussions on various types of cancers. Includes topics such as coping, support, clinical trials and treatment options. - CancerBACUP
Information and support from this UK organization which addresses many of the types of tumors. Includes access to online booklets and other resources.