Cancer prevention

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Carcinogenesis (lit.: creation of cancer) is the process of derangement of the rate of cell division.

The field of medicine concerned with the treatment of cancer is oncology. Cancer has become an important problem with the rise in life expectancy, as the abovementioned mutations become more likely the longer a person lives. Though great progress in treatment has been made, most cancers in advanced stages remain incurable and ultimately fatal.

In cellular model systems, cells are exposed to carcinogenic influences (chemicals, radiation). In these systems, the first signs of a cell developing into a tumor cell are:

Immortality. The usual number of cell divisions for a mammalian cell is 50-60 (cell senescence), then it ceases to divide. Tumor cells keep dividing forever.
Altered morphology.
Building of cellular clusters (Foci).
Loss of contact inhibition.
Low or no need for growth factors.

Items 2-4 (above) can sometimes be traced to mutations in genes that result in a disruption of cell adhesion. Some cell adhesion proteins are oncogenes.

Imperial Cancer Research Fund
News and information about the prevention, diagnosis and treatment of this condition. A UK charity site.
Wikicities: Cancer
An open-publishing wiki portal for those interested in this topic. Available for viewing or editing.
Topix.net: Cancer News
Headline news and content on related issues.
CancerSupport UK
An online directory of resources.
Cancer Site Finder.com
Offers a searchable database of cancer related websites with descriptions of each. Allows users to search by topic, feature, or quality standard.

Cancer prevention