Causes of skin cancer

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Carcinogenesis (lit.: creation of cancer) is the process of derangement of the rate of cell division.

The field of medicine concerned with the treatment of cancer is oncology. Cancer has become an important problem with the rise in life expectancy, as the abovementioned mutations become more likely the longer a person lives. Though great progress in treatment has been made, most cancers in advanced stages remain incurable and ultimately fatal.

A cell that degenerates into a tumor cell does usually not acquire all these properties at once, but its daughter cells are selected to build them. This process is called cellular evolution. A first step in the development of a tumor cell is usually a small change in the DNA, often a point mutation, which leads, among other things, to a genetic instability of the cell. The instability increases to a point where the cell loses whole chromosomes, or has double ones. Also, the DNA methylation pattern of the cell changes, activating and deactivating genes more or less at random. Cells that divide at a high rate, such as stem cells, show a higher risk of becoming tumor cells than those which divide less or not at all, for example neurons. If the initial tumor cell (or group of tumor cells) is not removed by the immune system, it will develop into cancer.

AtCancer
Gives access to a MEDLINE-related search engine, as well as to reference links.
The World Against Cancer
A conduit source consisting primarily of multi-lingual search engines.
CancerNews.com
Articles and links pertaining to many related topics.
Romanian Cancer League
Eastern European organization with aims of education, prevention, treatment, support and advocacy.
MyOwnBiopsy
Provides "translations" of cancer pathology reports from medical jargon into understandable lay terms.

Causes of skin cancer