Colon cancer symptoms
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Treatment of cancer typically involves surgery to remove tumors and nearby lymph nodes to which the cancer may have spread, combined with radiation therapy and/or chemotherapy. The latter two target cells in the body that are rapidly dividing. This includes the cancer cells but also certain healthy ones, which is the reason for the severe side effects of these treatments.
In cellular model systems, cells are exposed to carcinogenic influences (chemicals, radiation). In these systems, the first signs of a cell developing into a tumor cell are:
- Immortality. The usual number of cell divisions for a mammalian cell is 50-60 (cell senescence), then it ceases to divide. Tumor cells keep dividing forever.
- Altered morphology.
- Building of cellular clusters (Foci).
- Loss of contact inhibition.
- Low or no need for growth factors.
Items 2-4 (above) can sometimes be traced to mutations in genes that result in a disruption of cell adhesion. Some cell adhesion proteins are oncogenes.
Carcinogenesis (lit.: creation of cancer) is the process of derangement of the rate of cell division.
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- CancerFit
Details the activities of a program at the Sedona Racquet Club in Arizona. Designed to help survivors maintain good physical, emotional and spiritual fitness. - ChemoCare
Scott Hamilton’s chemotherapy site offers general treatment information for cancer patients. Sponsored by Ortho Biotech. - Yahoo Health: Radiation Therapy Center
Information including basic facts, what to expect and side effects. - The Cancer Letter
Periodical which supplies news and current information about the state of research and treatment. - Wikicities: Cancer
An open-publishing wiki portal for those interested in this topic. Available for viewing or editing.