Symptoms of throat cancer
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The term cancer is very broad and covers many different illnesses including:
- Carcinoma (arising from epithelial cells)
- Bladder carcinoma
- Breast cancer
- Cervical cancer
- Colorectal cancer (includes colon, rectum, anus, and appendix)
- Esophageal cancer
- Endometrial cancer (uterus)
- Hepatocellular carcinoma (liver)
- Laryngeal cancer
- Lung cancer
- Oral cancer
- Ovarian cancer
- Pancreatic cancer
- Prostate cancer
- Renal cell carcinoma (kidney)
- Skin cancer
- Stomach cancer
- Testicular cancer
- Thyroid cancer
- Sarcoma (arising from connective tissue and related)
- Gastrointestinal stromal cell tumor (GIST)
- Rhabdomyosarcoma (muscle)
- Osteosarcoma (bone)
- Hematological malignancies (blood and bone marrow)
- Leukemia
- Lymphomas
- Hodgkin's disease
- Non-Hodgkin's lymphoma
- Multiple myeloma
- Miscellaneous
- Brain tumor
- Melanoma, Moles and dysplastic nevi
- Teratoma
Malignant tumors such as carcinoma or sarcoma, lymphoma or leukemia originate from a cell or a group of cells in a multicellular organism that has several distinct properties:
- evading apoptosis
- Unlimited Growth Potential
- self-sufficiency of growth factors
- insensitivity to anti-growth factors
- increased cell division rate
- altered differentiation (specialization) ability
- no ability for contact inhibition
- ability to invade neighbouring tissue
- ability to build metastases
- ability to promote blood vessel growth (angiogenesis)
A cell that degenerates into a tumor cell does usually not acquire all these properties at once, but its daughter cells are selected to build them. This process is called cellular evolution. A first step in the development of a tumor cell is usually a small change in the DNA, often a point mutation, which leads, among other things, to a genetic instability of the cell. The instability increases to a point where the cell loses whole chromosomes, or has double ones. Also, the DNA methylation pattern of the cell changes, activating and deactivating genes more or less at random. Cells that divide at a high rate, such as stem cells, show a higher risk of becoming tumor cells than those which divide less or not at all, for example neurons. If the initial tumor cell (or group of tumor cells) is not removed by the immune system, it will develop into cancer.
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- Hologuides: Cancer
Information about various tumors in a links format. - Untangling The Web
Provides access to disability resources including those needed for cancer care support. - HCA Cancer Guides
General information including treatment options. - Shirley's Wellness Cafe
Promotes holistic and alternative approaches for cancer prevention and treatment. - Cancer Advice UK
Advice and information about diagnosis and treatment issues. Includes leaflets, book suggestions, links and support groups.