Throat cancer symptoms

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In medicine, cancer is a general term for any of a number of different diseases where some of the body's own cells divide in an uncontrolled manner. The resulting new cells can form a malignant tumor (a neoplasm) or propagate throughout the body.

A cell that degenerates into a tumor cell does usually not acquire all these properties at once, but its daughter cells are selected to build them. This process is called cellular evolution. A first step in the development of a tumor cell is usually a small change in the DNA, often a point mutation, which leads, among other things, to a genetic instability of the cell. The instability increases to a point where the cell loses whole chromosomes, or has double ones. Also, the DNA methylation pattern of the cell changes, activating and deactivating genes more or less at random. Cells that divide at a high rate, such as stem cells, show a higher risk of becoming tumor cells than those which divide less or not at all, for example neurons. If the initial tumor cell (or group of tumor cells) is not removed by the immune system, it will develop into cancer.

Treatment of cancer typically involves surgery to remove tumors and nearby lymph nodes to which the cancer may have spread, combined with radiation therapy and/or chemotherapy. The latter two target cells in the body that are rapidly dividing. This includes the cancer cells but also certain healthy ones, which is the reason for the severe side effects of these treatments.

  • On Top Of Cancer
    Links-based guide to Internet resource.
  • Wikicities: Cancer
    An open-publishing wiki portal for those interested in this topic. Available for viewing or editing.
  • Don't Say That Word
    Provides an online forum on cancer, information, personal stories, poetry and remembrance pages. Graphics-intensive.
  • COX-2 Inhibitors: Cancer
    Information about these treatment agents which is based on an educational grant from the Pharmacia company.
  • About.com: Cancer
    Presents general overview information on many of the main kinds of tumors. Includes news, doctor search, glossary and access to support hotlines.