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Wellness can include using scientifically-based tests and practices to maintain health, as in checking cholesterol, blood pressure, glucose, and other body indicators. Or it can include unproven practices, such as avoiding certain foods or taking certain vitamins or alternative medicines.

The subjective nature of "wellness" can be illustrated by the hypothetical example of an individual who avoids food additives and is selective in choosing foods to prolong health, but thinks nothing of getting in a car and driving hundreds of miles. Statistically, the known risk of mortality or morbidity from automobile usage is far greater than the risk of mortality or morbidity from food additives, but avoiding certain foods and food additives feels "healthy," whereas avoiding automobile use feels merely inconvenient.

Wellness has developed into a buzzword used by the Network Marketing and Multi-Level Marketing "communities" to sell unproven health supplements and quack cures.