Facial skin rash

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Poison ivy is apparently far more common now than when the Europeans first entered North America, because it has profited immensely from the "edge effect", enabling it to form lush colonies in such places.

Virginia creeper, Parthenocissus quinquefolia, vine can look like poison ivy. The younger leaves can come in groups of three but have a few more serrations along the leaf edge, and the leaf surface is somewhat wrinkled. Virginia creeper and poison ivy very often grow together, even on the same tree.

The skin rash, featuring fluid-filled blisters and reddened areas that itch intensely, is caused by an irritating oil, urushiol. Urushiol binds to skin cell walls, changing their configuration, so that the body's immune system no longer recognizes these cells as belonging to the body and attacks them as foreign. Some people are susceptible to the rash, and others aren't, but reactions can change during a person's lifetime. Someone who was formerly not subject to it may become very sensitive, and vice versa.

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