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Poison ivy is EXTREMELY hardy and very resistant to poisons. Some herbicides will not destroy the roots, allowing the plant to grow back the following year. Roundup and other grass killers do not affect poison ivy. Some people recommend using a brush killer.
Beware of dead poison ivy: it still has plenty of urushiol, and will give the same effect. Compare the thick vines of grape: no rootlets visible, to the vines of poison ivy: so many rootlets that the stem going up a tree looks furry.
Poison ivy looks like ivy. Each tendril of ivy ends in three leaves which are almond shaped. Color ranges from light green (usually the younger leaves) to dark green (mature leaves). Leaves can be as long as 10 or 12 inches long, but are usually 4-6 inches long when they are mature. Each leaf has a FEW teeth along its edge, and the leaf surface is SMOOTH. To compare, blackberry and raspberry leaves also come in threes, but they have MANY teeth along the leaf edge, and the top surface of their leaves are very wrinkled where the veins are. The stem and vine are smooth, brown and woody, while blackberry stems are green with thorns.
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Ask the Doctor - online medical forum (Q&A)for all aspects of skin / dermatology conditions.