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Virginia creeper, Parthenocissus quinquefolia, vine can look like poison ivy. The younger leaves can come in groups of three but have a few more serrations along the leaf edge, and the leaf surface is somewhat wrinkled. Virginia creeper and poison ivy very often grow together, even on the same tree.

When a person has been in contact with poison ivy, there are several measures that may be taken to prevent or lessen a rash. Zanfel and Tecnu are commercial preparations designed to 'unlock' urishiol from the skin. If applied within 20 minutes of exposure to poison ivy, these may be effective in completely preventing an outbreak. Zanfel, the more expensive of the two by far, is said to be effective at any stage of a poison ivy outbreak.

Urishiol is an oil and is not washed off by plain water. People have had success in lessening the rash by wiping the area clean with alcohol, or mild soap, in order to break down the oil. However, laundry detergent or Fels-Naphtha soap work much better, but vigorous rubbing is necessary. If you are desperate, you could also try wiping the area with other solvents, like acetone (nail polish remover). Some article advise against this because it will deprive your skin of moisturizers to protect you from the oil. However, the oil is obviously having an effect on your skin, and you can always put lotion on the area later.

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