Skin cancer rash

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The skin rash, featuring fluid-filled blisters and reddened areas that itch intensely, is caused by an irritating oil, urushiol. Urushiol binds to skin cell walls, changing their configuration, so that the body's immune system no longer recognizes these cells as belonging to the body and attacks them as foreign. Some people are susceptible to the rash, and others aren't, but reactions can change during a person's lifetime. Someone who was formerly not subject to it may become very sensitive, and vice versa.

Poison ivy (Toxicodendron radicans), in the family Anacardiaceae, is a woody vine that is well-known for its ability to produce urushiol, a skin irritant which for most people will cause an agonizing, itching rash.

Beware of dead poison ivy: it still has plenty of urushiol, and will give the same effect. Compare the thick vines of grape: no rootlets visible, to the vines of poison ivy: so many rootlets that the stem going up a tree looks furry.

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