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You can also physically pull up all the vines and roots but you must wear gloves and pants and a long sleeve shirt. DO NOT BURN poison ivy. The smoke particles carry the irritant and allow it to be inhaled; people that are extremely sensitive to poison ivy could die. Wrap the plants in a good garbage bag and bury them or dispose of them in a landfill.

Poison ivy is EXTREMELY hardy and very resistant to poisons. Some herbicides will not destroy the roots, allowing the plant to grow back the following year. Roundup and other grass killers do not affect poison ivy. Some people recommend using a brush killer.

Another solution is mixing 1/4 cup salt in 1 quart of water and put in a spray bottle. Spray the leaves of the poison ivy with this solution. NOTE: this will possibly kill any surrounding plant life if it gets a significant amount of salt water on it.