Canine cancer

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Carcinogenesis (lit.: creation of cancer) is the process of derangement of the rate of cell division.

For most of the cancers, it cannot be told which event was the initial cause. However, with molecular biology, it is possible to characterize the mutations within a tumor, and to a certain extent predict its behavior. For example, about half of the tumors are deficient in the tumor suppressor gene p53, also known as "the guardian of the genome". This is associated with poor prospects for the patient, since those tumor cells are unlikely to go into apoptosis (programmed cell death) after they are damaged by therapy. There are more mutations that make a tumor more malignant. Telomerase mutations enable a tumor cell to divide indefinitely. Other mutations enable the tumor to grow new blood vessels to feed it, or to detach from the surrounding tissue, spreading to other parts of the body.

In medicine, cancer is a general term for any of a number of different diseases where some of the body's own cells divide in an uncontrolled manner. The resulting new cells can form a malignant tumor (a neoplasm) or propagate throughout the body.

  • Target Tumors
    Information about targeted therapy approach in relation to a number of solid tumors.
  • Cancer.com
    Provides treatment information, support group listings, online education, decision-making resources, physician locator services and risk assessment tools.
  • USnews.com: Best Cancer Hospitals
    Ranking by the magazine of the fifty top cancer hospitals in the United States.
  • CancerCare
    Topics of interest to patients and their families including treatment side-effects, pain control, nutrition and bereavement.
  • Ladies Home Journal: Cancer
    Links to articles about skin and breast tumors.