High cholesterol

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It is interesting to note that the cholesterol in LDL cholesterol and the cholesterol in HDL cholesterol are identical. The only difference between the two is the carrier molecule (i.e. the lipoprotein).

Cholesterol is excreted from the liver in bile; under certain circumstances it can crystallise in the gallbladder to become a major constituent of gallstones, although lecitin and bilirubin gallstones can also occur.

Cholesterol is primarily synthesized from acetyl CoA through the HMG-CoA reductase pathway in the liver (~1 g/day), although other sites include the intestines, adrenal glands and reproductive organs.

  • WebMDHealth: Cholesterol Management Health Center
    Consumer health site for cholesterol, written and reviewed by doctors.
  • Living With Cholesterol: AHA
    Information for understanding the facts and reducing your risk factor of heart disease and stroke. Recipes available.
  • For Your Health - High Cholesterol Risks
    High cholesterol, lipids, lipoproteins, LDL HDL, triglycerides, and metabolic syndrome. Offers answers as to what it all means, and how to treat it.
  • Bupa
    Concise fact sheet explaining the causes, symptoms and treatment of cholesterol. Available for down loading in Adobe acrobat format.
  • Eat Fat, Be Healthy
    Information about genetically-caused heart disease due to small-particle LDL syndrome. Includes questions and answers, book excerpt and cardiac risk quiz.