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Medical conditions often require the use of a special diet that either contains or lacks certain chemicals. A person who has diabetes is often on a diet designed to carefully regulate their blood sugar level, sufferers of celiac disease must follow a gluten-free diet, the lactose-intolerant omit milk and dairy products, and people with kidney disease must follow a strict low-sodium diet to ease the strain on their kidneys.

Successful weight loss diet is all about energy in vs. energy out. If a person takes in fewer calories than he or she expends over a period of time, the person may burn fat and subsequently lose weight. To lose a pound of fat, one must create a caloric deficit of approximately 3,500 calories; therefore, if a person creates a deficit of 500 calories per day, the person will lose approximately 1 pound of fat per week. However, these numbers are strictly "in theory," and again what works for one person usually will not work for all.

VLCD's can be very successful but only when used over a 6-12 week period. Because the body is essentially starving, it is burning up its fat stores and lowering its metabolic rate. As soon as the diet ceases and normal food is consumed again, there is an immediate increase in weight. Short-term use of VLCDs (1-4 weeks) will have little, if any, benefit for the dieter as the increase in weight will negate the weight lost in the first place. Once the full course of the diet is finished, it is up to the successful dieter to maintain their current weight via exercise and sensible eating, otherwise they will put on weight again. VLCD's put a great deal of strain on a person's body, and should only be undertaken with medical consultation.

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